HIGH RESOLUTION MASS SPECTROMETER (HRMS)


  • Make: Waters, USA
  • Model: XEVO G2-XS QTOF
  • Faculty-in-Charge: Prof. Somnath Yadav
  • Email: hrms_crf@iitism.ac.in
  • Phone: 0326-223-5880

Equipped with dual electrospray ionization and atmospheric pressure chemical ionization (ESI/APCI), Dual atmospheric pressure chemical ionization and atmospheric pressure photo ionization (APCI/APPI) and atmospheric pressure solids analysis probe (ASAP), the Waters XEVO G2-XS QTOF High Resolution Mass Spectrometer (HRMS) at the Central Research Facility, IIT (ISM), Dhanbad can be used to detect the accurate mass of a wide range molecules such as small molecules, APIs as well as macromolecules. Coupled with the above, the Ultra High-Performance Liquid Chromatography (UPLC) system enables both quantitative and qualitative analysis of samples.


The key features of HRMS includes:


    Waters XEVO G2-XS QTOF HRMS:

    1.) Mass Range: 20 to 32,000 m/z in Quadrupole & 20 to 1,00,000 m/z in TOF.

    2.) Resolution: ≥ 45,000 FWHM for m/z 1000 and ≥ 35,000 FWHM for around 200 m/z.

    3.) Sensitivity: Full MS/MS mode ≤ 10 femtogram on column, at S/N ratio greater than 100:1

    ACQUITY UPLC H – CLASS PLUS SYTEM:

    1.) Quaternary operating pump(s) with an operating pressure of minimum 15000 psi

    2.) Flow rate range - 0.010 to 2.200 mL/min, in 0.001 mL increments

    3.) Flow rate accuracy: ±0.1 %.

Instrument Status : Running


Analysis Charge : Click Here